Inside a Cutting-Edge Vivarium: How Architects and Builders Create Labs for Humane Research

Two women in the laboratory

In the heart of the San Francisco Bay Area, a project has quietly come to life, playing a crucial role in the advancement of pharmacological research. This isn't about soaring towers or iconic facades—this project delves deep into the foundation of scientific progress. 

The confidential lab, designed by Flad Architects and brought to life by Landmark Builders, is a state-of-the-art vivarium that sets a new standard for humane animal care in research environments.

The Unique Challenges of Vivarium Design

Designing a vivarium is no small feat. These specialized labs must meet strict scientific, ethical, and operational standards. Unlike conventional laboratories, a vivarium requires a controlled environment where factors like cleanliness, temperature, humidity, and lighting are tightly regulated. 

For the team at Flad Architects, the challenge was not only to meet these stringent requirements but to create a space that supports the well-being of the animals used in research, particularly mice in this case.

This lab is tucked away in a basement, a location chosen for its ability to provide the necessary control over environmental variables. While this setting might seem challenging due to the absence of natural light, it actually offers a more stable environment for the animals, as it eliminates fluctuations caused by daylight. The architects needed to think creatively about how to make the space functional and humane, without relying on natural light, which is typically a key design element.

Balancing Functionality with Humane Standards

The primary goal of this project was to create a space where pharmacological research could be conducted under the highest standards of cleanliness and precision. At the same time, the facility had to ensure that the test animals, which play a critical role in research, were housed and treated humanely. 

The design features specialized lab spaces, procedure rooms, and a vivarium, along with break areas and offices for staff. Every element was carefully planned to support the researchers' work while maintaining a high standard of animal welfare.

To achieve this, Flad Architects employed materials and finishes that not only met scientific specifications but also enhanced the overall usability of the space. The design team considered factors such as ease of cleaning, durability, and the ability to maintain strict hygiene standards. These choices were essential in creating an environment that could withstand the demands of intensive research while protecting the well-being of the animals.

Capturing the Space: The Role of Photography

Documenting this project presented its own set of challenges. The confined spaces and tight corridors required a different approach to architectural photography. To capture the essence of the vivarium's design, I used an ultra wide lens, which allowed me to showcase the full scope of the spaces despite the limitations of the environment. The ultra wide lens was instrumental in highlighting the meticulous attention to detail in the design and construction of the lab.

A unique aspect of this photoshoot was the inclusion of a life-like stuffed white mouse, a subtle nod to the type of research conducted in the facility. This prop was carefully chosen to represent the animals used in the research while respecting the confidentiality of the ongoing projects. The use of this prop added a layer of storytelling to the images, connecting the design of the space with its purpose.

Meeting the Demands of Scientific Research

The success of any research facility depends on its ability to meet the rigorous demands of scientific inquiry. In this vivarium, the design had to accommodate various research activities, from routine procedures to complex experiments, all while maintaining an environment free of contaminants. The architects at Flad approached this challenge by integrating advanced HVAC systems, sterile materials, and precise control mechanisms throughout the facility.

Every detail was considered, from the placement of air filtration systems to the layout of the procedure rooms. The HVAC systems are designed to maintain a controlled environment, ensuring that temperature, humidity, and air quality remain consistent, crucial for both the animals' welfare and the integrity of the research. The use of sterile, easy-to-clean surfaces further minimizes the risk of contamination, which is vital in such a sensitive setting.

Another significant aspect of the design was the flow of traffic within the facility. The layout was meticulously planned to prevent cross-contamination between different areas of the lab. For example, the paths taken by staff when entering and exiting the vivarium were strategically designed to reduce the chances of introducing outside contaminants. This level of detail reflects the architects’ commitment to creating a space that supports the highest standards of scientific research.

The Human Element: Designing for Staff Well-Being

While the primary focus of the vivarium is on the research and the animals, the design also had to consider the people who work there. The architects included break areas and offices to provide the staff with spaces to relax and manage their day-to-day tasks. These areas were designed with comfort and functionality in mind, ensuring that staff can perform their duties effectively while having spaces that promote their well-being.

Incorporating these elements was not just about providing convenience; it was about acknowledging the importance of the human element in research. The architects understood that the people who work in the vivarium are key to the success of the research. By creating a supportive environment for them, the design helps foster a culture of excellence and care that extends beyond the lab and into the broader research community.

Innovative Solutions in a Confined Space

Given that the lab is located in a basement, the project required innovative solutions to maximize the available space. The design team had to think creatively to ensure that every square foot was used efficiently. The ultra wide lens used in the photography captures these clever design choices, highlighting how the space was optimized for both functionality and comfort.

One of the most notable solutions was the use of multi-purpose spaces. For example, certain areas of the lab can be quickly adapted to serve different functions, depending on the needs of the research at any given time. This flexibility is key in a confined environment, allowing the facility to meet the evolving demands of scientific research without the need for extensive renovations.


Flexible design is more than just a trend; it's a necessity in spaces where every inch counts. The ability to adapt spaces for multiple uses is what makes facilities like this one so effective.

The Role of Collaboration: Architects and Builders Working in Sync

The success of this vivarium project was also a testament to the collaboration between Flad Architects and Landmark Builders. Building a lab with such precise requirements demanded close coordination between the design and construction teams. From the earliest stages of planning to the final touches, every decision was made with input from both parties, ensuring that the vision for the space was fully realized.

This collaboration was particularly important given the complexity of the project. For example, the placement of specialized equipment and the integration of systems like HVAC required both teams to work closely together. The builders had to understand the design intent behind each element to execute it properly, while the architects needed to consider the practical challenges of construction. The result was a seamless integration of design and functionality, creating a lab that meets all the needs of modern research.

Parting Thoughts: Beyond the Aesthetics

Architecture is often celebrated for its aesthetic qualities, but projects like this vivarium remind us that functionality can be just as important—if not more so. This lab, tucked away in a basement, may not catch the eye with its exterior, but its design plays a vital role in advancing scientific knowledge and ensuring that research is conducted under the best possible conditions.

By focusing on the specific needs of a pharmacological research facility, Flad Architects and Landmark Builders created a space that is both highly functional and humane. This project exemplifies how architecture can contribute to scientific progress, not just by providing a space for research, but by ensuring that every aspect of that space supports the work being done within it. The attention to detail, from the materials used to the layout of the space, highlights the critical role that design plays in research environments.

In documenting this project, the use of an ultra wide lens was essential in capturing the full scope of the design. The photographs showcase not just the physical space, but the thought and care that went into every aspect of its creation. This project may be confidential, but its impact on the field of pharmacological research is undeniable, and it stands as a testament to what can be achieved when architects and builders work together towards a common goal.

Key Takeaways

  • Strict Standards: The vivarium lab was designed to meet rigorous scientific and humane standards, ensuring a controlled environment for research.

  • Basement Location: The lab’s basement location was chosen to maintain stable environmental conditions, critical for both research integrity and animal welfare.

  • Collaborative Effort: The success of the project was due to close collaboration between Flad Architects and Landmark Builders, ensuring seamless integration of design and functionality.

  • Flexible Design: Innovative design solutions, such as multi-purpose spaces, were employed to maximize functionality in a confined space.

  • Ultra Wide Lens Photography: The use of an ultra wide lens was essential to capture the full scope of the lab’s intricate design, highlighting the thoughtful planning and execution.

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